I don't see much chance to avoid being blown out in this one. First, it's the second night of a back-to-back on the road, with the Lakers having two days off. Second, the Cavs don't have the size or muscle up front to counter Bynum and Gasol. The Lakers will pound it into the post all night. The Cavs couldn't control Love, Aldridge or Jefferson, so I don't see any chance of neutralizing Bynum and Gasol.
The Lakers are only hitting 24% of their 3-point shots, so the Cavs need to drop down and double the Lakers' big men and take their chances on the 3-pointers. They also need to double down when Derek Fisher has the ball, as he's only hitting 34% from the field.
The Lakers are only scoring 95 ppg but their opponents are averaging less than 90 ppg, so they're getting it done with defense, rebounding, and Kobe. I don't think the Cavs will have much success taking it to the hole against these guys.
The Lakers are huge and their starting lineup averages 11 years in the NBA. They have some injuries to their bench, but as long as their big three are healthy the Cavs should present few problems. I don't see them beating the Cavs by 55 points like they did at this time last year, but I'll be surprised if this one is ever in doubt.