"I just don't want someone to have a needle and give me HIV and I don't want to get shot or stabbed."
Pattinson recalled one time where a group of girls approached him bleeding from scratches they had just opened up on their necks.
"They were like, 'We did this for you' … I didn't know what to say — 'Thank you, guys?'"
Pattinson said he feels vulnerable at big film events such as premieres, where he could be the target of an overly obsessive fan or even a terror attack.
He admits struggling to come to terms with fame since the release of the first movie, which grossed more than $350m worldwide.
He has difficulty coping with so many people trying to "ambush" him in public and at home.
He said he has come to accept the attention, but would be prepared to give away acting away for his first passion — music — if the fans ever became too much